Cardiac Arrhythmia Classifications


Warburg meets epigenetics | Science

Not all cells follow the textbook procedure for cellular respiration in the presence of oxygen. Instead, certain cells (T cells and cancer cells) tend to run glycolysis even when oxygen is abundant. This article suggests that the aceytl-CoA products from pyruvate DH are used to acetylate, or open certain frames of DNA for gene transcription and cell specialization. Cool right!?

Warburg meets epigenetics | Science


Chance meeting leads to creation of antibiotic spider silk

A chance meeting between a spider expert and a chemist has led to the development of antibiotic synthetic spider silk.

After five years’ work an interdisciplinary team of scientists at The University of Nottingham has developed a technique to produce chemically functionalised spider silk that can be tailored to applications used in drug delivery, regenerative medicine and wound healing.

The Nottingham research team has shown for the first time how ‘click-chemistry’ can be used to attach molecules, such as antibiotics or fluorescent dyes, to artificially produced spider silk synthesised by E.coli bacteria. The research, funded by the Biotechnology and Biological Sciences Research Council (BBSRC) has been published in the online journal Advanced Materials.

The chosen molecules can be ‘clicked’ into place in soluble silk protein before it has been turned into fibres, or after the fibres have been formed. This means that the process can be easily controlled and more than one type of molecule can be used to ‘decorate’ individual silk strands.

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Prime evidence of the need for collaboration in the advancement of science 🤓