By constantly reminding the immune system what the parasite that causes leishmaniasis looks like, a persistent infection keeps the immune system on alert against new encounters, even while it carries the risk of causing disease later in life

Persistent Infection Keeps Immune System on Alert, Leading to Long-term Protection

Which is better? Long-term immunity with the cost of persistent infection OR complete riddance at the cost of becoming infected again

I think I agree that control persistent infection probably has the most robust evolutionary advantage here as if you are in an area where you are exposed to one of these pathogens it is probably best to harbor long term immunity. 

It would be interesting to determine in a follow-up study if location/exposure to conspecific external pathogens increases the duration that the immune system reserves these pathogens. 


Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )


Connecting to %s